Laser Therapy rau tinnitus thiab tsis hnov ​​lus

① Nws feem ntau ntseeg tau tias cov saw hlau ua pa ua lub luag haujlwm tseem ceeb hauv kev kho laser. Laser zog nyob rau hauv lub liab thiab ze-infrared spectrum muaj peev xwm nkag mus rau cov ntaub so ntswg. Nws txhawb cov mitochondria hauv cov hlwb los tsim lub zog los ntawm kev tsim cov adenosine triphosphate (ATP).

② Mitochondria, uas yog lub zog ntawm txhua lub roj teeb, lawv metabolize roj thiab tsim lub zog rau cov hlwb hauv daim ntawv ntawm ATP.

③ Nws tau raug tshaj tawm tias qhov raug LLLT nce ATP ntau lawm. Kev tsim cov ATP ntau ntxiv tuaj yeem ua rau muaj zog ntawm cov cellular metabolism, txhawb kev rov qab los ntawm kev puas tsuaj, rov ua kom cov hlwb rov qab mus rau lub xeev noj qab haus huv, thiab thim rov qab ntau yam degenerative.

④Rau kab mob pob ntseg, nws tau tshaj tawm tias kev siv laser qis tuaj yeem hloov cov ntaub so ntswg collagen hauv cochlea. Tshwj xeeb tshaj yog nyob rau hauv qab daus daim nyias nyias. Tsis tas li ntawd, LLLT muaj txiaj ntsig zoo rau kev rov qab los ntawm cochlear plaub hau hlwb tom qab mob alopecia thiab tuaj yeem ua rau cov hlwb nce ntxiv.

⑤ Proliferate, synthesize ATP thiab collagen, tso tawm qhov kev loj hlob, txhawb cov ntshav hauv zos hauv pob ntseg, thiab qhib lub tshuab kho. Lub pob ntseg sab hauv yog stimulated los ntawm photochemical thiab photophysical stimulation ntawm cov plaub hau cell mitochondria.

Tag nrho ntawm 107 tus neeg, suav nrog cov txiv neej thiab poj niam hnub nyoog nruab nrab ntawm 18 thiab 65 xyoo, muaj idiopathic thiab refractory tinnitus, tau cuv npe hauv txoj kev tshawb no. Kev nrhiav neeg ua haujlwm tau ua los ntawm cov vev xaib online thiab cov ntawv xov xwm, tsom rau cov tib neeg uas muaj cov tsos mob ntawm ib sab lossis ob sab tinnitus. Cov txheej txheem cais tawm suav nrog cov kab mob endocrine, ntshav qab zib, ntshav siab, mob qog noj ntshav, thiab rog rog.

Pab pawg 1 (n=11) tau txais kev kho mob nrog kev kho lub tshuab nqus tsev thiab qib qis laser kho (LLLT). Lub laser tsis tau teem rau 100 mW rau txhua qhov chaw laser, nrog wavelengths ntawm 660 nm (3 me ntsis; lub teeb liab) thiab 808 nm (3 qhov chaw; lub teeb infrared). Kev kho lub tshuab nqus tsev tau siv rau 3 feeb nyob ib ncig ntawm pob ntseg siv MP7 hom (nruam) ntawm qhov siab ntawm −120 mbar. Kev tswj hwm Transcochlear (piv txwv li, hauv thaj av tom qab auricular) ntawm LLLT thiab kev kho lub tshuab nqus tsev tau ua tiav los ntawm kev siv ib qho khoom siv tsim nyog rau kev teeb tsa sib txawv.

Thaum cov ntaub ntawv yav dhau los tau pom cov txiaj ntsig zoo ntawm LLLT rau kev kho mob tinnitus, cov kev tshawb fawb soj ntsuam cochlear LLLT feem ntau siv cov qib laser.<7.5 mW. Contrary to these findings, our study revealed no significant effects when increasing the power to 100 mW per spot for both 660 nm and 808 nm wavelengths, whether combined with vacuum therapy or flunarizine dihydrochloride. Notably, the lack of significance was demonstrated by the absence of statistically significant differences in Total Tinnitus Handicap Inventory (THI) scores between the placebo (Group 1) and treatment groups (Groups 2 and 3).

Although literature on cochlear LLLT using laser power levels >7.5 mW tsis tshua muaj, cov qib no feem ntau tau tshaj tawm hauv kev tshawb fawb transmeatal LLLT. Ib qho kev tshawb fawb los ntawm Shiomi et al. koom nrog 38 refractory tinnitus cov neeg mob kho nrog 830-nm transmeatal LLLT ntawm sab nraud auditory kwj dej ntawm cochlea siv 40 mW ntawm lub hwj chim, ib lub lim tiam rau kwv yees li kaum lub lis piam. Tom qab kev kho mob, cov neeg koom nrog ntsuas qhov ntim ntawm tinnitus, lub sijhawm ntev, thiab tsis xis nyob ntawm tsib-point scale. Txawm hais tias tsuas yog 26% ntawm cov neeg mob tau pom tias muaj kev txhim kho hauv cov qauv ntsuas, kev txhim kho txog li 55% mus rau 58% tau pom nyob rau lub sijhawm, ntim, thiab kev ntxhov siab, tawm tswv yim photobiomodulation yog ib qho kev xaiv zoo rau kev kho cov neeg mob refractory tinnitus.